Furthermore, changes in behavior occurred simultaneously with changes in tail position and ear shape, and the appearance of a white muzzle, forehead blaze, and white shoulder hair. The white color pattern on the head is similar to many domestic animals (Belyaev 1979) (Figs. 1.1 and 1.2). The most dog-like foxes had white spots and patterns on their heads, drooping ears, and curled tails and looked more like dogs than the foxes that avoided people. The behavioral and morphological (appearance) changes were also correlated with corresponding changes in the levels of gender hormones. The tame foxes had higher levels of the neurotransmitter serotonin (Popova et al., 1975). Serotonin is known to inhibit some kinds of aggression (Belyaev, 1979), and serotonin ~levels are increased in the brains of people who take Prozac (fluoxetine).