what I think:
either Glenn or Maggie (or both) will die getting out of this pickle they have gotten themselves into, or perhaps, more shockingly, Rick or Carl (hey Robert kirkman said no one was safe LOL). Daryl or more then likely, Abraham will step up as group leader.
Beth is either saved by Gabriel, or perhaps, Tyreese and Carol. They get the drop before they arrive that Terminus is not what they thought it was and swoop in and save everyone (using walkers as a weapon).
Rick's group decides to accompany Abraham's group to Washington DC where they find that the Doc is lying about his knowledge, angered, Abraham kills him. It doesn't matter because DC is lost anyway.