I dont think anyone here (to my knowledge) has anything against mixed breed dogs, quite a few including myself have a mixed breed. I think most of us here are against intentionally mixing breeds though. if you seriously beilieve that by mixing a bloodhound with the more athletic border collie will eventually after several dozen generations, produce the best search and rescue breed the world has ever seen; and you are willing to take the amount of time, spend the amount of money, and get the number of people to help you that would be required for such an undertaking to succeed...awesome!! go for it. but most if not all of the intentional mixes today (labradoodles, alsatian shepalutes, cackapoos, etc) were a sadly succesfull attempt by a person or persons to convince others that they had created a new breed that everybody would want. they did it to make money and most have no concern for the dogs they are breeding and producing, and even less concern for all the other dogs in the world. they are feeding on the ignorance of the world, knowing that if they call it NEW or RARE then tons of people will be willing to pay large amounts for them. they arent breeding based on health or temperament and they arent placing puppies in homes based on interviews, background checks and contracts. they are placing them in the homes of anyone ignorant enough to beleive they are worth the price, hypoallergenic, superior in this way or that.
I love mixed breeds, often they are healthier than a purebred (though if you go through a good breeder and do your research you can get a very healthy purebred) and no 2 mixed breeds look alike. thats one thing I dont get...I have heard a lot of people say they want a labradoodle or maltoodle or whatever because they are different, they dont look like the Smiths lab or the Stephens rottweilers or little Sallies family german shepherd. that alone is not a justifiable reason to get a dog or pick a breed. besides, as I said no 2 mixed breeds look the same, maybe similar but less similar than 2 labs or 2 german shepherds.
you want a mixed breed? your local shelter has a bunch!