It doesn't bother me. A few years back, me and my dad were watching a dog show together. It was one of the first ones I had ever sat down and really paid attention too. One of the handlers came on and was talking about her dogs. She said, "They really are pretty bitches." Me and my dad looked at eachother and started laughing. I had been so used to hearing it as a "dirty word," that it just sounded hilarious.
But no, it doesn't bother me because that's what they are. A bitch. The word was turned into something else long after it had it's original meaning.
Just like "gay" or "queer."