Great suggestions so far. I would also ask the breeder for water from there instead of introducing a pup to different water while traveling. An xpen is always smart to have when traveling with pup/s. Easy store, set up and take down, and the pups are likely to potty faster and easier than on leash in a strange place with strangers. I would set the x pen up in non dog places, especailly avoiding pet areas as others have already stated. I would bring extra sheets or blankets to hang on the x pen to block vision if they were worried at all. Extra towels and paper towels are a must when traveling with pups along with a some 1/2 water, 1/2 vineager solutions to help with any clean ups. A trash bag to put soiled blankets, towels or mats helps too and a smaller trash bag to confine dirty paper towels if you have to do a quick clean up with no trash bins around to dispose off it. Extra collars and leashes, it would be nice if the breeder could do a bit of training before hand on leading and crate training before hand a must. A blanket to put over the crate in the vehicle in case you need to cover them to keep them quiet or from getting car sick.
Agree with BB, I never let dogs loose in any hotel room until I have checked in and around/under the beds and the rest of the room. I too have found everything from rotting food, pills, illegal drugs and once a condom. I travel with a good flash light for that and for pottying after the sun goes down.